MAISEN is a web tool dedicated to annotation of bacterial and archeal nucleotide sequences. It allows you to browse structural and functional annotation hits from various databases in one place.

Currently, the MAISEN pipeline consists of the following programs:


  • Structural Annotation
    1. Prodigal
    2. tRNAscan-SE
    3. ARAGORN

  • Functional Annotation
    1. DIAMOND with NBCI non-redundant protein database
    2. DIAMOND with UniProtKB/Swiss-Prot database
    3. HMMER with Conserved Domains database


If you would like to cite MAISEN please refer to the following work:

Dziurzynski M, Decewicz P, Ciuchcinski K, Gorecki A, Dziewit L. Simple, Reliable, and Time-Efficient Manual Annotation of Bacterial Genomes with MAISEN. Methods Mol Biol. 2021;2242:221-229. doi: 10.1007/978-1-0716-1099-2_14. PMID: 33961227.

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